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Array Technique

  • In the past few decades, molecular diagnostics has made great efforts to develop rapid multi-analysis methods. New diagnostic techniques have been developed due to advances in the sequencing of the human genome and all encoded proteins. Among various technological solutions for diagnostic applications, array technology has attracted the attention of a wide range of research groups and industries and greatly affected the methods of disease discovery and genome understanding.

    Introduction of Array Technique

    The microarray consists of a series of ordered probes, which include nucleic acids, nucleic acid analogs (such as peptide nucleic acids (PNA) and locked nucleic acids (LNA), proteins, carbohydrates, tissues, cells, and polymers. Most arrays currently in use contain hundreds or thousands of probes. The value of this technology is that it allows highly parallel measurement and has the advantages of high throughput, miniaturization, and high speed. This has led to important applications of microarray technology in the development of medical research, drug resistance, pharmacogenomics, and molecular diagnosis. Among all kinds of in vitro diagnostic (IVD) methods, array technique is the one that provides the highest throughput for the determination of many analytes in relatively few samples and is listed as one of the most important detection technology modules.