Recent Entries

  • Making the Most of SARS-CoV-2 Antibody Responses in the Post-Pa

    The COVID-19 pandemic, which emerged at the end of 2019, may have receded from public consciousness, but its impact continues to reverberate. Over the past three years, countries worldwide have grappled with multiple waves of widespread infection. Although many nations have now established immunity ...
  • New Insights Into the Pathogenesis and Diagnosis of Rheumatoid

    The hallmark of rheumatoid arthritis (RA) is erosive arthritis, an autoimmune disease that ultimately results in joint deformities and functional loss. It can also be complicated by pulmonary disease, cardiovascular disease, malignant tumors, and depression.   The etiology of RA remains uncle...
  • Investigation of Pharmacokinetics/pharmacodynamics (PK/PD) of A

    Pharmaceutical corporations and academic institutions have invested significant time, money, and effort in recent years to increase the accuracy and applicability of in vitro screening technology, which measures the biological activity and physicochemical characteristics of substances. Animal models...
  • Half-life Assay by Bleach-chase

    The half-life assay by bleach-chase is applicable to fluorescently tagged proteins and can be applied to multiple proteins and time points in living cells. Furthermore, this method is suitable for high-throughput protein half-life determination, making it easier to screen candidate protein drugs b...
  • Polysome Profiling

    mRNAs have varying translation efficiency, which can alter rapidly during adaptation to various environmental conditions such as cellular stressors and microbial infections. Polysome profiling, or the examination of mRNAs associated with polysomes, has been widely utilized to study post-transcriptio...