Recent Entries

• Technology for Non-IgG Antibody Characterization

  by Gemini Smith June 16, 2023
  Several techniques are available to evaluate the quality, quantity, and function of the therapeutic non-IgG antibodies produced, such as enzyme-linked immunosorbent assay (ELISA), flow cytometry, immunoblotting, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Besides, our innov...

• Polysialylation Based Half-Life Extension

  by Gemini Smith June 16, 2023
  PSA (polysialic acid) is found on the surface of a variety of cells, including mammalian cells; thus, it is a biocompatible and biodegradable natural polymer that is highly hydrophilic and has no identified receptors in the body.The prolonged residence of polysialylated conjugates increases the spec...

• Explore into Pharmacokinetics/pharmacodynamics (PK/PD) of Antib

  by Gemini Smith June 16, 2023
  In the past few decades, both pharmaceutical companies and academia have spent much financial resources and energy to improve the practicability and accuracy of in vitro screening technology that can test the biological activity and physicochemical properties of compounds. However, the study of pote...

• Capture Antibody and Detection Antibody

  by Gemini Smith June 16, 2023
  Sandwich enzyme-linked immunosorbent assays (ELISAs) are the most frequently used ELISA format. It requires the use of matched antibody pairs, whereby each antibody is specific for different non-overlapping epitopes on the antigen. Firstly, one known as the capture antibody is coated onto the surfac...

• SARS-CoV-2 DNA vaccine service

  by Gemini Smith June 16, 2023
  The most effective way to control the spread of the COVID-19 epidemic is still vaccines. In order to develop potent vaccines to prevent SARS-CoV-2 virus infection, researchers have competed on the track to develop various types of vaccines. As a new type of vaccine, DNA vaccine has some unique advan...