Sildamax 100mg (which contains sildenafil) is generally effective whether taken on an empty stomach or with food. However, taking it on an empty stomach may lead to quicker absorption and potentially faster onset of action. If you consume it with a heavy meal, especially one high in fat, Sildamax 100mg might slow down the absorption process. For the best results, it’s often recommended to follow the specific instructions provided by your healthcare provider or those given with the medication. If you have any concerns or experience side effects, discussing them with a healthcare professional would be a good idea.