Recent Entries

  • Detoxification matters! They can prolong their life by 21%

    Protein is an important component of all cells and tissues of the human body. However, abnormal protein activities in the body may cause problems, such as increasing the risk of cancer and making people age faster.   On July 28, a research report titled "Rewiring of the ubiquitinated proteome...
  • Antibody Drugs Might Be A Powerful Weapon Fighting COVID-19

    Antibody drugs are an important part in the field of biotechnology-based pharmaceuticals. The use of antibodies to diagnose and treat diseases has long been a goal pursued by pharmaceutical scientists. Antibody binding to target antigens has advantages of high specificity, efficacy, and safety,...
  • Analysis The Future Development of In Vitro Drug-induced Cardio

    In vitro drug-induced cardiotoxicity determination is a key step in clinical drug discovery. For this reason, the use of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) is promising. However, the ability of a single hiPSC-CM to mimic natural heart tissue in structur...
  • Introduction to Top-down Proteomics Technology

    Biological mass spectrometry-based proteomics analysis methods mainly include Bottom-up and Top-down methods. Ÿ Bottom-up is a traditional method that (enzymatically) digests a mixture of large fragments of proteins into small fragments of peptides and then analyzes them. It is widely use...
  • The main function of the Mitochondria

    Energy conversion Mitochondria are the site of oxidative metabolism in eukaryotes, and the place where carbohydrates, fats and amino acids are finally oxidized to release energy. The common pathway of final oxidation that mitochondria is responsible for is the tricarboxylic acid cycle and oxidative...