A vaccine is a pharmaceutical product that has been artificially and specially treated to contain components of pathogens that not only retain characteristics that can be recognized by the immune system (antigenicity), but also destroy their lethality. In addition, vaccines contain some auxiliary components, such as adjuvants, preservatives, stabilizers, etc. Therefore, there are very strict requirements for their transportation.
Since vaccines are produced from the factory to vaccination, in which they go through several circulation, transportation and storage stages, coupled with their sensitivity to temperature. Therefore, in order to ensure the stability and antigenicity of vaccines, the cold chain throughout the process is particularly important. Generally speaking, liquid vaccines need to be refrigerated at 2 to 8°C, while lyophilized vaccines need to be stored frozen at -20°C. In order to ensure low temperature, there are also many professional equipments in vaccine transportation and storage, including low-temperature cold storage, ice row freezer, general cold storage, refrigerated trucks, refrigerators, refrigerated backpacks, etc.

In the process of safe vaccine transportation, special vehicles for transportation and temperature monitoring systems are essential. Perfect hardware is a prerequisite to ensure that vaccines are intact in the cold chain transportation. If you want to do a good job in cold chain transportation of vaccines, the most basic thing is to have excellent hardware equipment. Like refrigerated trucks, vehicles and refrigerators need to be strictly controlled to ensure that they are intact, which is the basis of cold chain transportation of vaccines. If there is a problem in the cold chain transportation, what kind of impact will it have?
First of all, the vaccine will be inactivated because the antigenic components of the vaccine will be inactivated under unsuitable storage conditions. Even after vaccination, the body will not be able to produce immunity when it encounters pathogens, so the vaccination will be in vain.
Secondly, depending on the type of vaccine given, vaccines that are inactivated due to superheating are the same as fake drugs that are ineffective, and the consequences of vaccination are incalculable and can lead to death in serious cases. Another point is that the effects of ineffective vaccines may not be obvious in a short period of time, but the potential long-term risks are immeasurable, and when most people are not immune to a disease or multiple diseases, it is bound to greatly increase the rate of outbreaks and the risk of epidemics.
Finally, ineffective vaccines may have direct toxic effects. Although there are no clear cases of injury or death directly caused by hyperthermia vaccination at home or abroad, we cannot completely rule out the possibility that hyperthermia vaccines may have "direct toxic effects".