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Xanax is the single most prescribed psychiatric drug in the United States; belong to the benzodiazepines group of drugs. A brand name of alprazolam, Xanax is generally prescribed for anxiety linked with depression, generalized anxiety disorder, and panic disorder. The drug is used to treat anxiety disorder and is available in various forms which include the extended-release tablets, tablets, disintegrating tablets and liquid forms. Alprazolam is also available in several generic types and the brand Xanax was approved in 1981 by the Food and Drug Administration and together with the extended-release tablets are manufactured by Pfizer. Jazz Pharmaceuticals produce the orally disintegrating tablets while Alprazolam Intensol the liquid form is made by West-Ward Pharmaceuticals.
The way Xanax is taken depends on the condition it is used for, the form being taken and your age. Your doctor is in the right position to decide how it should be taken, so Xanax should be used as recommended by your doctor. Depending on the prescription of your doctor, the drug is ideally taken one, two to four times daily. The tablets form should be taken with water while the markings in the calibrated dropper can be used for various doses and the concentrated oral form can be mixed with semisolid food or liquid and taken according to your doctor’s prescription. The tablet form should not be broken, crushed or chewed but swallowed as a whole with water.
The best way to use Xanax is by following your doctor or pharmacist prescription. The drug is used to treat panic disorder as well as anxiety disorder by acting on the central nervous system and the brain to produce the calming effect that reduces the impact of these conditions. Xanax is also known to treat panic disorder linked with agoraphobia or without it reducing the number of panic attacks that occur. Panic disorder is a medical condition where an individual experiences frequent panic attacks. These attacks are often characterized by the brief duration of discomfort or intense fear. Before using Xanax, ensure you are well-advised about the side effects, and when you notice the occurrence of any reaction, promptly contact your doctor.
Before using Xanax, do make sure you are aware of the side effects. If you are allergic to alprazolam or you have other allergies, discuss with your doctor before using Xanax because the drug may contain some inactive ingredients that may trigger certain conditions. For people that have acute narrow-angle glaucoma, you should not take Xanax. Taking the medication reduces your ability to focus because it makes you drowsy if you are debilitated or aged, as such do not drive, operate machinery or involve in activities that require your alertness. Using Xanax can be addictive and habit-forming, do not use it longer than the recommended duration of your doctor or take higher doses. If you have a drug abuse history or alcoholism, depression, Kidney or Liver problems, breathing problems such as Asthma or history of seizures or Epilepsy, ensure you tell your doctor before taking Xanax.
Using Xanax has some side effects; however, your doctor might have known that it will benefit your condition before prescribing it for you. If any of the side effects persist longer than expected or worsens, consult your doctor immediately. Your dosage may have to be reduced or the form you are using changed. Dizziness, drowsiness, increase production of saliva are some of the side effects that are known to be caused by Xanax. The side effects often occur when you start using the drug, and they go away in short periods, so there is nothing to wrong about. You can also manage some of the side effects such as light-headedness and dizziness by getting up slowly when standing up from a lying or seated position.
Most individuals prefer using Xanax to treat anxiety than using therapy because it is instrumental in alleviating the condition. It is more like an easy fix for anxiety for most people. Anxiety causes an imbalance of chemicals in the brain. When Alprazolam is taken, it works on the central nervous system and brain to create a sense of relaxation and calm; it also works as a muscle relaxant and a sedative. It works in the body by slowing down or reducing the effects of panic and anxiety; however, the brain becomes used to the presence of the drug over time which can reduce the functioning of the GABA receptor worst than it was before using Xanax.
Alprazolam is a drug that belongs to the benzodiazepine family and is used for the treatment of anxiety states, especially in panic attacks, agoraphobia, panic attacks and intense stress.
It is sold under a generic name or under different trade names depending on the country, all with identical effects, only practically changing the excipient or the design of the pill / tablet. It has a hypnotic effect (promoting sleep in the short term) and works by decreasing the excitement of the brain.
Alprazolam has sedative, hypnotic, and anticonvulsant properties, but the most notable effect is anxiolytic. However, due to its addictive potential and the development of tolerance after a relatively short period of a few weeks, its administration is recommended only in short-term treatments.
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Occasional anxiety is a normal part of life. However, those suffering from anxiety disorder have intense, excessive and persistent fears very frequently in everyday situations.
Frequently, in anxiety disorders there are repeated episodes of sudden feelings of intense anxiety and fear or terror that peak in a matter of minutes (panic attacks).
Feelings of panic and anxiety are sometimes very difficult to control as they are disproportionate to reality and can last a long time, leading to interference with daily activities.
Agoraphobia belongs to the spectrum of anxiety disorders and consists of the fear of places and situations capable of generating panic or the feeling of being trapped, ashamed or defenseless.
Panic disorder consists of several episodes of unexpected feelings of very intense anxiety or fear that can reach very high levels in a matter of minutes (panic attacks). The person may experience sensations of catastrophe, dyspnea, chest pain, or heart palpitations.
Once these attacks happen, the patient will cause the person to worry and watch for them to happen one more time and will try to avoid the situations in which they have happened previously.
Generalized anxiety disorder is nothing more than intense and repetitive worry and anxiety about routine activities and situations. Worry is very dissociated from reality, making it difficult to control, affecting the way the person feels physically. This disorder can be associated with other anxiety disorders or depression.
The fundamental indication for xanax is in anxiety-type disorders. Among these disorders we can highlight panic disorder with or without agoraphobia, and generalized anxiety disorder.
Adaptive disorders, those in which some type of derived and explicable symptoms appear from the experience of a specific event or psychosocial stress, are also often treated with alprazolam and other benzodiazepines.
This is not a formal indication. However, xanax has been used in depressive disorders that are associated with anxiety disorders. However, this application should be evaluated and applied with great caution in patients with suicidal ideations and severe depression, as it can potentially enhance symptoms.
One of the indications for alprazolam is found in patients with social phobia, helping to reduce the level of anxiety at the prospect of being exposed to other people.
Alprazolam has also been shown to be useful in treating the discomfort and anxiety generated by chemotherapy in patients who must undergo it due to some type of tumor.
Let’s go back to the 1960s for a moment. Psychiatric treatments were the new norm and the new fashion of the day. Everyone was talking about it, and many were undergoing such treatments. It was the mainstream thing to do at that point.
Researchers decided to develop ways to help people who were suffering from insomnia, mostly due to anxiety as the main cause. That’s when Dr. Leo Sternbach created benzodiazepine (which was Librium) in 1956.
His goal was simple for the public to understand: to create a safer, theoretically less addictive alternative to traditional tranquilisers of the time such as barbiturates. Dr Sternbach is credited with creating Klonopin, Valium and other drugs of a similar nature.
The first patent for alprazolam was approved and granted during the 70’s. It was developed by J.B. Hester at the former Upjohn Company laboratories (which later became part of Pfizer Inc). Alprazolam, the generic name for the later Xanax, was first made with the idea of aiding sleep as well as acting as a muscle relaxer.
By the 1970s, the most famous prescription drug in the United States was Valium, and Alprazolam was following the heels of it. Although Valium was very popular, it was not patented for the treatment of anxiety and panic. That’s when the creators of the early Xanax found an opportunity to market it.
It was launched by Upjohn company in 1981; a perfect timing as the third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), published by the American Psychiatric Association in 1980 had included anxiety disorders in the clinical category. The FDA approved the drug in 1981. The patent came just before the Valium patent was about to expire.
Dr. David Sheehan was one of the first researchers to demonstrate this drug’s effectiveness in treating panic disorders, anxiety and so on. In fact, its effects are known to be rapid as well as not losing effectiveness over time. After its first two years on the market, Xanax had become the new antidote of the day in the United States.
Alprazolam is a drug with psychoactive or psychotropic properties that is classified within anxiolytics, substances used to treat anxiety and its manifestations. Among the anxiolytics, it is part of the benzodiazepines, these being one of the most popular types of psychoactive drugs and consumed by the population (being much safer, more effective and with fewer side effects than their predecessors, barbiturates).
In the same way as the rest of the benzodiazepines, the mechanism of action of xanax consists of its interaction with GABA, one of the most important neurotransmitters for the inhibition of the central nervous system.
Xanax acts by stimulating positively on GABA A receptors, thus favoring the inhibition of action potentials in neurons. In other words, it reduces the activity of neurons in certain parts of the brain. This activity is completed dominatingly on the limbic system (profoundly activated in anxiety) and the cerebral cortex.
In the specific case of alprazolam, we are dealing with an intermediate-acting benzodiazepine, which implies that it takes a shorter time to start to take effect in the body compared to a long-acting one, but at the same time that its effects last for less time than these. , and vice versa in the case that we compare it with a short-acting one.
Its effect lasts between 12 and 24 hours approximately. This represents a great advantage since the probabilities of dependence and addiction to the drug are reduced. So small doses are necessary to achieve a longer effect, without the need for it to take too long to take effect.